Authors: Macarthur KL, Forouhar F, Wu GY Sarcoidosis is an inflammatory disease characterized by non-caseating granulomas in the absence of other autoimmune processes, infectious diseases, or foreign agents. The etiology of sarcoidosis is not completely understood. Several organ systems can be affected, of which the most frequently involved include the lungs and lymph nodes. Intra-abdominal [...]
The antimalarials chloroquine and hydroxychloroquine have been used for the treatment of inflammatory diseases for more than 60 years. Even today new indications evolve due to the complex mode of action of these compounds. Due to the fear of side effects, especially irreversible retinopathy, their use is often limited. These side-effects, however, are a consequence [...]
Get New York AlertsHuffington Post (blog)Further studies showed conclusively that asthma increased and that there was a spike in certain lung-scarring diseases like sarcoidosis. …and more » Source: sarcoidosis – Google News
Semin Respir Crit Care Med 2010; 31: 485-493DOI: 10.1055/s-0030-1262216ABSTRACTThis review focuses on current knowledge of the QOL (quality of life) and HS (health status) of sarcoidosis patients. The QOL and HS of sarcoidosis patients are impaired and symptoms are a cause of this impairment. Fatigue appears to be the major problem in sarcoidosis patients. QOL [...]
Semin Respir Crit Care Med 2010; 31: 474-484DOI: 10.1055/s-0030-1262215ABSTRACTThe synthesis of vitamin D is altered by the granulomatous inflammation of sarcoidosis leading to increased production of 1, 25-dihydroxyvitamin D. Mounting evidence suggests that vitamin D is an immunomodulating hormone that inhibits both antigen presentation by cells of the innate immune system, and the cytokine release [...]
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Authors: Stepieà  J, Domagaà Âa-Kulawik J, Chadzyà Âski R, Kupis W, Chazan R A 50-year old patient was admitted to the hospital with hoarseness persisting for two weeks. Chest computed tomography revealed enlargement of lymph nodes in the aortopulmonary window. The bronchoscopy did not show any abnormalities, in transbronchial fine needle aspiration biopsy no diagnostic material was [...]
We present two cases of sarcoidosis with rheumatologic manifestations. Our intent is to encourage a multidisciplinary, translational approach to meet the challenges and difficulties in understanding and treating sarcoidosis.[...]© Thieme Medical PublishersGet connected:Table of contents  |  Abstract  |  Full text (Source: Seminars in Respiratory and Critical Care Medicine) Source: MedWorm: Sarcoidosis
Semin Respir Crit Care Med 2010; 31: 452-462DOI: 10.1055/s-0030-1262213ABSTRACTOcular disease occurs in approximately a third of sarcoidosis patients. The rate of disease varies around the world, with Japanese sarcoidosis patients having ocular disease in more than 70% of cases. If untreated, ocular disease can lead to permanent visual impairment, including blindness. The most common manifestation [...]