Archive for category Treatment'

Predominantly bullous pulmonary sarcoidosis complicated by aspergillosis (article in French)

Fajac A, Valeyre D, Sadoun D, Tandjaoui A, Battesti JP (Source: The Aspergillus Website – articles) Source: MedWorm: Sarcoidosis

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Hemoptysis in sarcoidosis. Apropos of 6 cases including 4 with fatal outcome (article in French)

Lemay V, Carette MF, Parrot A, Bazelly B, Grivaux M, Milleron B (Source: The Aspergillus Website – articles)

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Source: MedWorm: Sarcoidosis

No evidence of altered alveolar macrophage polarization, but reduced expression of TLR2, in bronchoalveolar lavage cells in sarcoidosis

Conclusions:
Overall, there was no evidence for alveolar macrophage polarization in sarcoidosis. However, there was a reduced TLR2 mRNA expression in patients with Lofgren’s syndrome, which may be of relevance for macrophage interactions with a postulated sarcoidosis pathogen, and for the characteristics of the ensuing T cell response. (Source: Respiratory Research)

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Letter to the Editor: Limited long‐term efficacy of intravitreous anti‐VEGF pharmacotherapy in sarcoidosis complicated by peripapillary choroidal neovascular membrane

(Source: Acta Ophthalmologica) Source: MedWorm: Sarcoidosis

Long-term outcome of double-lung and heart-lung transplantation for pulmonary hypertension: a comparative retrospective study of 219 patients [Original articles]

Conclusions: In patients with end-stage PH, good long-term survival rates were obtained using either DLT or HLT. However, these results were achieved with preferential use of HLT in patients with right heart failure or CSPS. Obliterative bronchiolitis-related death was less common with HLT than with DLT. (Source: European Journal of Cardio-Thoracic Surgery)

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Long-term preserved renal function of a patient with mass-forming granulomatous interstitial nephritis by biopsy-based steroid therapy

Abstract  In 2001, a 41-year-old Japanese woman was referred to our hospital because of severe renal dysfunction and fever of unknown
origin. On admission, her serum creatinine was 8.7 mg/dL, urine protein was 0.3 g/day, and urine β2-microglobulin was 81,007 Î¼g/day. Computed tomography (CT) scans showed bilateral contracted kidneys with a mass projecting
from the lower pole of the [...]

Pulmonary hypertension in sarcoidosis, caused by extrinsic compression of major pulmonary vessels

We present the case of a young man with sarcoidosis complicated by fatal pulmonary hypertension due to extrinsic compression of the major pulmonary vessels by mediastinal granulomatous inflammation and lymphadenopathy. (Source: Respiratory Medicine CME) Source: MedWorm: Sarcoidosis

Lymphocytopenia-associated sarcoidosis: CD4+ T-cell hypo-responsiveness to IL-2 and lectin

We report the case of an 18-year-old man, with pulmonary sarcoidosis, treated by corticoids, who developed cryptococcal meningitis. A CD4+ T-cell defect was simultaneously discovered, which was not influenced by corticoid arrest, persisted following infection resolution and control of sarcoidosis. In vitro experiments were performed in parallel, demonstrating a restricted CD4+ T-cell proliferation hypo-responsiveness to [...]

Lithoptysis in coincidence with chronic pulmonary sarcoidosis

Abstract: A case report describing a rare cause of stones expectoration – lithoptysis – in a 57-year-old female with chronic pulmonary sarcoidosis. During the follow-up two episodes of lithopysis were observed. Chronic pulmonary sarcoidosis may be a rare cause of lithoptysis. (Source: Respiratory Medicine CME)

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Chronic Diseases: Who’s killing us, and how?

MICROBIOLOGIST GARTH NICOLSON interview, (Sudbury, Ontario Aug. 30, 2008). Will YOUR doctor tell you about weaponized mycoplasma? About engineered mycoplasma pathogens in vaccines? Or will he or she treat your symptoms, hook you up for life (or death) on high-priced (and often dangerous) drugs? What’s the real story of Chronic Fatigue Syndrome, Gulf War Syndrome, [...]