Development of a Sarcoidosis Murine Lung Granuloma Model Using Mycobacterium sodA.

Authors: Swaisgood CM, Oswald-Richter K, Moeller SD, Klemenc JM, Ruple LM, Farver CF, Drake JM, Culver DA, Drake WP Sarcoidosis is characterized by noncaseating granulomas containing CD4+ T cells with a Th1 immunophenotype. While the causative antigen(s) is not known, independent studies have noted molecular and immunologic evidence of mycobacterial virulence factors in sarcoidosis specimens. [...]

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