Markers of fibrosis and inflammation in exhaled breath condensate (EBC) and bronchoalveolar lavage fluid (BALF) of patients with pulmonary sarcoidosis – a pilot study.

Conclusions: FOB does not significantly affect levels of airway inflammation and fibrosis markers present in EBC before and after FOB; they were also comparable to the concentrations marked by BALF. The lack of correlation between markers levels in EBC and BALF indicates that these methods are not equivalent. Due to repeatibility, and less invasive, simple [...]

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Clinical features and outcome of acquired haemophilia A. Interim analysis of the Düsseldorf Study.

Conclusion: This monocenter study demonstrates that control of life-threatening bleeding, eradication of the inhibitor, and induction of tolerance to endogenous FVIII have significantly improved the clinical outcome of acquired haemophilia A. Our data also suggest a shift in underlying disorders associated with acquired haemophilia A, whereby, in comparison to published studies, a relative increase in [...]

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Renal Transplantation in Patients with Sarcoidosis: A French Multicenter Study.

CONCLUSIONS: Our results indicate that renal transplantation may be carried out safely in transplant candidates with sarcoidosis. Recurrence is not rare and is likely to affect graft outcome. These results fully justify a specific clinical and histologic monitoring mainly during the early posttransplant period. PMID: 20671220 [PubMed - as supplied by publisher] (Source: Clinical Journal [...]

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Sarcoidosis in U.S. black women: Data from the Black Women’s Health Study.

CONCLUSION: This study confirms previous reports of high incidence and prevalence of sarcoidosis among black women, as well as the extent of extra-pulmonary disease, frequent need for steroid therapy, and co-morbid conditions in this population. The prospective identification of sarcoidosis cases from a defined population will enable a valid assessment of risk factors for incident [...]

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‘MP Study Results,’ Cpt. Tom Perez’s Porto Presentation

This is the HD video of Cpt. Tom Perez’s presentation at the 6th International Congress on Autoimmunity, in Porto, Portugal, Sept 10-14, 2008, titled: “Bacteria Induced Vitamin D Receptor Dysfunction in Autoimmune Disease: Theoretical and practical Implications for Interpretation of Serum Vitamin D Metabolite Levels” A written transcript of this presentation is available from URL: [...]

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[Selective lacrimal sac biopsy for external dacryocystorhinostomy : A clinical pathological study.]

CONCLUSION: External dacryocystorhinostomy with selective biopsy for atypical clinical and intraoperative findings allows safe diagnosis and management of potentially life-threatening lacrimal lesions. PMID: 20535481 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) MedWorm Message: Register for MedMatcha, MedWorm’s medical advertising network, and receive $5 free advertising. Source: MedWorm: Sarcoidosis

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The continuing search for Mycobacterium tuberculosis involvement in sarcoidosis: a study on archival biopsy specimens

Conclusion: Our results do not support the hypothesis that M. tuberculosis complex infection is involved in the pathogenesis of sarcoidosis. However, we stress the importance of excluding mycobacteriosis in the diagnostic workup of sarcoidosis patients. Please cite this paper as: Svendsen CB, Milman N, Rasmussen EM, Thomsen VØ, Andersen CB and Krogfelt KA. The continuing [...]

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Different Activity of the Biological Axis VEGF-Flt-1 (fms-Like Tyrosine Kinase 1) and CXC Chemokines between Pulmonary Sarcoidosis and Idiopathic Pulmonary Fibrosis: A Bronchoalveolar Lavage Study

Conclusions. Our data suggest that increased expression of Flt-1 and downregulation of CXCL12α in IPF may further support the hypothesis of a different angiogenetic profile between fibrotic and granulomatous diseases. However, further studies are needed in order to better investigate these enigmatic diseases. (Source: Clinical and Developmental Immunology) MedWorm Message: Get the very latest Swine [...]

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